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UC SAN DIEGO COURSE - NEU221: GENETICS AND EPIGENETICS OF BRAIN DEVELOPMENT

 

 


 

Rosenfeld Laboratory

  Publications 

 

 

 

 

 

 

 

 

      



Zhou W, Zhu P, Wang J, Pascual G, Ohgi KA, Lozach J, Glass CK, Rosenfeld MG.

Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation.

Mol Cell. 2008 Jan 18;29(1):69-80.

PMID: 18206970 [PubMed - in process]

 

Representative Publications: (2007)

Signaling and epigenetic regulation of pituitary development.

Curr Opin Cell Biol. 2007 Dec;19(6):605-11. Epub 2007 Nov 7. Review.

PMID: 17988851 [PubMed - indexed for MEDLINE]

 

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron.

Nature. 2007 Nov 15;450(7168):415-9. Epub 2007 Oct 10.

PMID: 17928865 [PubMed - indexed for MEDLINE]

 

A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation.

Mol Cell. 2007 Aug 17;27(4):609-21.

PMID: 17707232 [PubMed - indexed for MEDLINE]

 

Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.

Science. 2007 Jul 13;317(5835):248-51.

PMID: 17626886 [PubMed - indexed for MEDLINE]

 

Molecular physiology of pituitary development: signaling and transcriptional networks.

Physiol Rev. 2007 Jul;87(3):933-63. Review.

PMID: 17615393 [PubMed - indexed for MEDLINE]

 

 

Opposing LSD1 complexes function in developmental gene activation and repression programmes.

Nature. 2007 Apr 19;446(7138):882-7. Epub 2007 Mar 28.

PMID: 17392792 [PubMed - indexed for MEDLINE]

 

 

Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors.

Cell. 2007 Feb 9;128(3):505-18.

PMID: 17289570 [PubMed - indexed for MEDLINE]

 

Representative Publications: (2006)

 

A breaking strategy for topoisomerase IIbeta/PARP-1-dependent regulated transcription.

Cell Cycle. 2006 Nov;5(22):2557-60. Epub 2006 Nov 15.

PMID: 17106262 [PubMed - indexed for MEDLINE]

 

Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.

Genes Dev. 2006 Oct 1;20(19):2739-53.

PMID: 17015435 [PubMed - indexed for MEDLINE]

 

 

Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG.

Related Articles, Links

A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.
Science. 2006 Jun 23;312(5781):1798-802.
PMID: 16794079 [PubMed - indexed for MEDLINE]

 

Rosenfeld MG, Lunyak VV, Glass CK.

Related Articles, Links

Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response.
Genes Dev. 2006 Jun 1;20(11):1405-28. Review.
PMID: 16751179 [PubMed - indexed for MEDLINE]

 

Olson LE, Tollkuhn J, Scafoglio C, Krones A, Zhang J, Ohgi KA, Wu W, Taketo MM, Kemler R, Grosschedl R, Rose D, Li X, Rosenfeld MG.

Related Articles, Links

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.
Cell. 2006 May 5;125(3):593-605.
PMID: 16678101 [PubMed - indexed for MEDLINE]

 

Zhu P, Baek SH, Bourk EM, Ohgi KA, Garcia-Bassets I, Sanjo H, Akira S, Kotol PF, Glass CK, Rosenfeld MG, Rose DW.

Related Articles, Links

Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway.
Cell. 2006 Feb 10;124(3):615-29.
PMID: 16469706 [PubMed - indexed for MEDLINE]

 

Wang Z, Qi C, Krones A, Woodring P, Zhu X, Reddy JK, Evans RM, Rosenfeld MG, Hunter T.

Related Articles, Links

Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance.
Cell Metab. 2006 Feb;3(2):111-22.
PMID: 16459312 [PubMed - in process]

Representative Publications: (2005)

Lunyak VV, Rosenfeld MG 

 

 No Rest for REST: REST/NRSF Regulation of Neurogenesis.
Cell. 2005 May 19

 

Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH.

 

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.
Nature. 2005 Apr 14;434(7035):921-6.

 

Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR Jr, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J Jr, Chen J, Xiao RP, Cheng H, Fu XD.

 

ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle.
Cell. 2005 Jan 14;120(1):59-72.

Representative Publications: (2004)

Ju BG, Solum D, Song EJ, Lee KJ, Rose DW, Glass CK, Rosenfeld MG.

 

Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway.
Cell. 2004 Dec 17;119(6):815-29.

 

Korzus E, Rosenfeld MG, Mayford M.

 

CBP histone acetyltransferase activity is a critical component of memory consolidation.
Neuron. 2004 Jun 24;42(6):961-72.

Perissi V, Aggarwal A, Glass CK, Rose DW, Rosenfeld MG.

 

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.
Cell. 2004 Feb 20;116(4):511-26.

Li X, Rosenfeld MG.

 

Transcription: origins of licensing control.
Nature. 2004 Feb 19;427(6976):687-8. No abstract available.

Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, Sawyers CL.

 

Molecular determinants of resistance to antiandrogen therapy.
Nat Med. 2004 Jan;10(1):33-9. Epub 2003 Dec 21.

 

Representative Publications: (2003)

 

Gold DA, Baek SH, Schork NJ, Rose DW, Larsen DD, Sachs BD, Rosenfeld MG, Hamilton BA.

 

RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways.
Neuron. 2003 Dec 18;40(6):1119-31.

 

Briata P, Ilengo C, Corte G, Moroni C, Rosenfeld MG, Chen CY, Gherzi R.

 

The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs.
Mol Cell. 2003 Nov;12(5):1201-11.

 

Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG.

 

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.
Nature. 2003 Nov 20;426(6964):247-54. Erratum in: Nature. 2004 Jan 15;427(6971):265.

 

 

 Archive: Representative Publications: (1995-2002)

 

 

 

 

LABORATORY OF M. GEOFFREY ROSENFELD

Investigator, Howard Hughes Medical Institute
Room 345, CMM West, School of Medicine
9500 Gilman Drive, Mail Code 0648
University of California, San Diego
La Jolla, California 92037-0648

Telephone: 858-534-5858
FAX: 858-534-8180

E-mail:
mrosenfeld@ucsd.edu

 

 

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Main address: University of California, San Diego, 9500 Gilman Dr., La Jolla, CA 92093-0648
Send questions, comments and suggestions about the Rosenfeld Lab website to: itrosenfeld@ucsd.edu

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