Representative
Publications: (1995-2002)
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Kioussi C, et al. dentification of a Wnt/Dvl/beta-Catenin
--> Pitx2 pathway mediating cell-type-specific proliferation during
development.
Cell. 2002 Nov
27;111(5):673-85. |
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Kumar, V., et al. and M. G. Rosenfeld, (2002)
Transcription corepressor CtBP is an NAD+ -regulated
Dehydrogenase. Molecular Cell 10:1-20. (2002)
[PDF] |
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Hermanson, O., et al. N-CoR controls differentiation of
neural stem cells into astrocytes. Nature 419:934-939 (2002).
[PDF] |
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Lunyak, V.V., et al. Corepressor-Dependent Silencing of
Chromosomal Regions Encoding Neuronal Genes. Science
(Research Article) 298(5599):1747-52 (2002).
[PDF] |
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Kioussi, C., et al. Identification of a Wnt/Dvl/b-catenin
® Pitx2 Pathway Mediating Cell Type-Specific Proliferation during
Development. Cell 111(5):673-85 (2002).
[PDF] |
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Li X, et al. Tissue-specific regulation of retinal and
pituitary precursor cell proliferation. Science 297:1180-3 (2002).
[PDF] |
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Baek, S.H., et al. Regulated Exchange of N-CoR
Corepressor and Tip60 Coactivator Complexes Links Expression by NF-kB and b-Amyloid
Precursor Protein. Cell 110:55-67 (2002).
[PDF] |
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McEvilly, R.J., et
al. Transcriptional Regulation of Cortical Neuron Migration by POU Domain Factors. Science
295:1528-1532 (2002).
[PDF] |
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Klappacher, G.W., et al. An Induced Ets Repressor Complex
Regulates Growth Arrest during Terminal Macrophage Differentiation. Cell
109:169-180 (2002).
[PDF] |
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Scully, K., et al. Allosteric effect of Pit-1 DNA binding
sites dictate long-term repression in pituitary cell type specification. Science
(Research Article) 290:1127-1131
(2000).
[PDF] |
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Jepsen, K., et al. Combinatorial roles of the nuclear
receptor co-repressor in transcription and development. Cell
102:753-763 (2000). [PDF]
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Lin, C.R., et al. Pitx2 regulates lung asymmetry,
cardiac positioning, and pituitary and tooth morphogenesis. Nature
401:279-282 (1999). [PDF]
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Dasen, J.S., et al. Reciprocal interactions of Pit-1 and
GATA-2 mediate signaling gradient-induced determination of pituitary cell
types. Cell 97:587-598 (1999).
[PDF] |
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Nolte, R.T., et al. Ligand binding and co-activator
assembly of the peroxisome proliferator-activated receptor-gamma. Nature
(Article) 395:137-143 (1998).
[PDF] |
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Westin, S., et al. Interactions controlling the assembly
of nuclear-receptor heterodimers and co-activators. Nature 395:
199-202 (1998).
[PDF] |
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Ryan, A.K., et al. Pitx2 determines left-right asymmetry
of internal organs in vertebrates. Nature (Article) 394:545-551
(1998).
[PDF] |
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Xu L., et al. Signal-specific coactivator domain
requirements for Pit-1 activation. Nature 395: 301-306 (1998).
[PDF] |
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Kurokawa R., et al. Differential use of CREB binding
protein-coactivator complexes. Science 279(5351):700-703 (1998).
[PDF] |
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Korzus E., et al. Transcription factor-specific
requirements for coactivators and their acetyltransferase functions.
Science 279(5351):703-707 (1998).
[PDF] |
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Torchia, J.,et al. The transcriptional coactivator,
p/CIP, binds CBP and mediates nuclear-receptor function. Nature
(Article) 387: 677-684 (1997).
[Abstract] |
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Heinzel, T., et al. A complex containing N-CoR, mSin3,
and histone deacetylases mediates transcriptional repression. Nature
(Article) 387:43-48 (1997).
[PDF] |
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McEvilly, R.J., et al. Requirement for Brn-3.0 in
differentiation and survival of sensory and motor neurons. Nature
384:574-577 (1996).
[Abstract] |
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Sornson, M.W., et al. Pituitary lineage determination by
the Prop-1 homeodomain factor defective in Ames dwarfism. Nature
(Article) 384:327-333 (1996).
[Abstract] |
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Kamei, Y., et al. A CBP integrator complex mediates
transcriptional activation and AP-1 inhibition by nuclear receptors.
Cell 85:403-414 (1996).
[PDF] |
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Kurokawa, R., et al. Polarity-Specific activities of
retinoic acid receptors determined by a co-repressor. Nature
377:451-454 (1995).
[Abstract] |
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Erkman, L., et al. Role of transcription factors Brn-3.1
and Brn-3.2 in auditory and visual system development. Nature
381:603-606 (1996).
[Abstract] |
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Hörlein,
A.J., et al. Ligand-independent repression by the thyroid hormone receptor
mediated by a nuclear receptor co-repressor. Nature (Article)
377:397-404 (1995).
[Abstract] |